Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBX7 | O95931 | 1/20 | 0.38 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.38 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.38 |
| ▸ | CDY1; CDY1B | Q9Y6F8 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 7/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 7/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 7/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 6/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25310581 | 0.85 | NPC1 (0.40) | CBX7CDYL2CDYLCDY1; CDY1BCHRM4 | |
| SCHEMBL25867651 | 0.82 | SIGMAR1 (0.40) | CBX7CDYL2CDYLCDY1; CDY1BCHRM4 | |
| SCHEMBL20117054 | 0.82 | CHRM2 (0.53) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL30476259 | 0.73 | USP30 (0.44) | ALDH1A1 | |
| SCHEMBL30988527 | 0.72 | OPRM1 (0.56) | CHRM4CHRM5CHRM1CHRM3CHRM2 | |
| SCHEMBL31426196 | 0.72 | CRBN (0.54) | CHRM2ALDH1A1TSHR | |
| SCHEMBL31426197 | 0.72 | CRBN (0.54) | CHRM2ALDH1A1TSHR | |
| SCHEMBL614398 | 0.70 | SIGMAR1 (0.47) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 | |
| SCHEMBL5546317 | 0.70 | SIGMAR1 (0.44) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 | |
| SCHEMBL29704410 | 0.70 | SIGMAR1 (0.47) | CBX7CDYL2CDYLCDY1; CDY1BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134656-A1 | PEPTIDYL NITRILE COMPOUND AND USE THEREOF | 上海壹典医药科技开发有限公司 | 2023-07-20 | — | — | WO | disclosed |
| CN-116332937-A | Dipeptidyl peptidase I inhibitors and uses thereof | 杭州邦顺制药有限公司 | 2023-06-27 | — | — | CN | disclosed |