SCHEMBL25866451

SCHEMBL25866451

CCCCCCCCCC(CCCCCCC)CCCCCCCN(CCCCCCCC(=O)OC(CCCCCCC)CCCCCCCCC)CC(O)c1nccn1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.36
MAPK1 P28482 4/20 0.36
LMNA P02545 6/20 0.35
ALDH1A1 P00352 1/20 0.35
PPARG P37231 2/20 0.34
GMNN O75496 3/20 0.33
NPSR1 Q6W5P4 3/20 0.33
MEN1 O00255 2/20 0.33
HSP90AA1 P07900 2/20 0.33
BLM P54132 2/20 0.33
KMT2A Q03164 2/20 0.33
NR1H4 Q96RI1 2/20 0.33
PRKCA P17252 1/20 0.33
PRKCE Q02156 1/20 0.33
PRKCQ Q04759 1/20 0.33
PRKCD Q05655 1/20 0.33
GLA P06280 1/20 0.33
PMP22 Q01453 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PPARA Q07869 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25866454 0.97 MAPT (0.38) MAPTMAPK1LMNAALDH1A1PPARG
SCHEMBL25126372 0.77 ALDH1A1 (0.41) MAPTMAPK1LMNAALDH1A1GMNN
SCHEMBL25125663 0.77 ALDH1A1 (0.41) MAPTMAPK1LMNAALDH1A1GMNN
SCHEMBL23483274 0.76 ALDH1A1 (0.40) MAPTMAPK1LMNAALDH1A1PRKCA
SCHEMBL25866170 0.76 ASAH1 (0.47) MAPTMAPK1LMNAALDH1A1PPARG
SCHEMBL25125883 0.76 MAPK1 (0.40) MAPTMAPK1LMNAALDH1A1GMNN
SCHEMBL30338183 0.76 ALDH1A1 (0.46) MAPTMAPK1LMNAALDH1A1GMNN
SCHEMBL25125923 0.76 ALDH1A1 (0.46) MAPTMAPK1LMNAALDH1A1GMNN
SCHEMBL24771055 0.75 ALDH1A1 (0.41) MAPTMAPK1LMNAALDH1A1GMNN
SCHEMBL3007645 0.75 LMNA (0.49) MAPTMAPK1LMNAALDH1A1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023126006-A1 CATIONIC LIPID CONTAINING FUNCTIONAL GROUP ON SIDE CHAIN, AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2023-07-06 WO disclosed