Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | DRD2 | P14416 | 3/20 | 0.38 |
| ▸ | DRD3 | P35462 | 3/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 7/20 | 0.38 |
| ▸ | JAK1 | P23458 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | DTYMK | P23919 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25429671 | 0.82 | HSD11B1 (0.42) | MAP2K1JAK3DRD4DRD2DRD3 | |
| SCHEMBL30509700 | 0.82 | HSD11B1 (0.42) | MAP2K1JAK3DRD4DRD2DRD3 | |
| SCHEMBL30509709 | 0.80 | CYP11B2 (0.39) | MAP2K1DRD4DRD2DRD3HSD11B1 | |
| SCHEMBL25426035 | 0.80 | CYP11B2 (0.39) | MAP2K1DRD4DRD2DRD3HSD11B1 | |
| SCHEMBL25307353 | 0.78 | CYP11B2 (0.38) | MAP2K1JAK3DRD4DRD2DRD3 | |
| SCHEMBL25427796 | 0.76 | HSD11B1 (0.41) | MAP2K1JAK3HSD11B1JAK1POLB | |
| SCHEMBL30509712 | 0.76 | HSD11B1 (0.41) | MAP2K1JAK3HSD11B1JAK1POLB | |
| SCHEMBL25428242 | 0.75 | HSD11B1 (0.42) | MAP2K1JAK3HSD11B1JAK1POLB | |
| SCHEMBL30509683 | 0.75 | HSD11B1 (0.42) | MAP2K1JAK3HSD11B1JAK1POLB | |
| SCHEMBL12509444 | 0.73 | HSD11B1 (0.62) | MAP2K1DRD4DRD2DRD3HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |