Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.39 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6891746 | 0.79 | RIPK1 (0.50) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL20163215 | 0.77 | RIPK1 (0.49) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL11751773 | 0.77 | CYP2D6 (0.48) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL19963515 | 0.77 | CYP2D6 (0.48) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL21790795 | 0.76 | CYP2D6 (0.44) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL11818840 | 0.75 | LMNA (0.63) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL7316409 | 0.73 | IDO1 (0.46) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL9858066 | 0.73 | POLB (0.46) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL6098836 | 0.73 | CYP3A4 (0.46) | CYP2D6LMNARIPK1CYP3A4MAPT | |
| SCHEMBL3631502 | 0.73 | HTT (0.61) | CYP2D6LMNARIPK1CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023141225-A1 | FUSED HETEROCYCLES AS 5-HT2A RECEPTOR AGONISTS | ONSERO THERAPEUTICS INC. (US) | 2023-07-27 | — | — | WO | disclosed |