Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25244706 | 0.80 | L3MBTL1 (0.43) | KMT2AMEN1MAPTL3MBTL1LMNA | |
| SCHEMBL29651126 | 0.80 | KMT2A (0.76) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL1746797 | 0.80 | KMT2A (0.76) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL17179359 | 0.80 | L3MBTL1 (0.43) | KMT2AMEN1L3MBTL1BRD4 | |
| SCHEMBL12700349 | 0.79 | KMT2A (0.42) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL29443986 | 0.78 | L3MBTL1 (0.41) | KMT2AMEN1ALDH1A1L3MBTL1BRD4 | |
| SCHEMBL15902421 | 0.78 | L3MBTL1 (0.41) | KMT2AMEN1ALDH1A1L3MBTL1BRD4 | |
| SCHEMBL26581229 | 0.76 | NR4A2 (0.60) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL21227557 | 0.74 | NPSR1 (0.37) | KMT2AMEN1MAPTALDH1A1L3MBTL1 | |
| SCHEMBL18418493 | 0.73 | UCHL1 (0.40) | KMT2AMEN1L3MBTL1BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023134608-A1 | FUSED RING COMPOUNDS SERVING AS HPK1 INHIBITORS | 微境生物医药科技(上海)有限公司 | 2023-07-20 | — | — | WO | disclosed |