Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 1/20 | 0.31 |
| ▸ | EED | O75530 | 1/20 | 0.31 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.31 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20689528 | 0.82 | L3MBTL1 (0.35) | NPSR1CYP2C19CYP2C9L3MBTL1HTR6 | |
| SCHEMBL20689530 | 0.74 | USP30 (0.33) | NPSR1CYP2C19CYP2C9L3MBTL1 | |
| SCHEMBL25866682 | 0.74 | KMT2A (0.49) | MAPTL3MBTL1ALDH1A1LMNAPOLB | |
| SCHEMBL31195162 | 0.71 | ACLY (0.40) | NPSR1CYP2C19CYP2C9L3MBTL1HTR6 | |
| SCHEMBL9166140 | 0.70 | CYP2C9 (0.43) | NPSR1CYP2C19CYP2C9MAPTALDH1A1 | |
| SCHEMBL13548419 | 0.70 | CYP2C9 (0.46) | NPSR1CYP2C19CYP2C9MAPTL3MBTL1 | |
| SCHEMBL15059343 | 0.69 | KRAS (0.48) | L3MBTL1HTR6LMNAKMT2AMEN1 | |
| SCHEMBL27397888 | 0.68 | CYP2C9 (0.44) | NPSR1CYP2C19CYP2C9MAPTL3MBTL1 | |
| SCHEMBL14164202 | 0.68 | BUB1 (0.40) | NPSR1CYP2C19MAPTL3MBTL1HTR6 | |
| SCHEMBL19445998 | 0.68 | BUB1 (0.42) | NPSR1CYP2C19L3MBTL1HTR6LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190241575-A1 | TYK2 INHIBITORS AND USES THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190241575-A1 | TYK2 INHIBITORS AND USES THEREOF | TYK2, JAK2, JAK1 | NPSR1 4287/4885CYP2C19 3767/4885CYP2C9 4115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.