Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
| ▸ | VDR | P11473 | 1/20 | 0.35 |
| ▸ | NQO2 | P16083 | 4/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | BRAF | P15056 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.31 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | PARK7 | Q99497 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23797765 | 0.81 | IDO1 (0.39) | ADRA2BNQO2ALDH1A1LMNAMAPT | |
| SCHEMBL25873234 | 0.81 | POLB (0.44) | ARVDRALDH1A1LMNAMAPT | |
| SCHEMBL23709737 | 0.80 | FERMT2 (0.41) | ADRA2BALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL18403936 | 0.79 | ADRA2B (0.37) | ADRA2BNQO2KDRALDH1A1LMNA | |
| SCHEMBL13718267 | 0.77 | ADRA2B (0.38) | ADRA2BKDRALDH1A1MAPK1TDP1 | |
| SCHEMBL15384343 | 0.77 | MAPT (0.42) | ADRA2BALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL9024554 | 0.77 | NCF1 (0.44) | ADRA2BNQO2ALDH1A1 | |
| SCHEMBL23798296 | 0.77 | BACE1 (0.41) | ADRA2BNQO2HRH4BACE1BACE2 | |
| SCHEMBL9024162 | 0.77 | ADRA2B (0.36) | ADRA2BNQO2ALDH1A1LMNAMAPT | |
| SCHEMBL22174845 | 0.75 | ADRA2B (0.35) | ADRA2BNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | C4 THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11691972-B2 | Compounds for targeted degradation of BRD9 | BRD9, BRD1, BRWD1 | ADRA2B 4207/4885AR 2060/4885VDR 3618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.