Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 7/20 | 0.61 |
| ▸ | ACHE | P22303 | 7/20 | 0.61 |
| ▸ | APP | P05067 | 5/20 | 0.61 |
| ▸ | CTNNB1 | P35222 | 4/20 | 0.50 |
| ▸ | TCF7L2 | Q9NQB0 | 4/20 | 0.50 |
| ▸ | USP1 | O94782 | 1/20 | 0.48 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | UBE2N | P61088 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.46 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25309780 | 0.87 | APP (0.67) | BCHEACHEAPPCTNNB1TCF7L2 | |
| SCHEMBL25867149 | 0.86 | APP (0.66) | BCHEACHEAPPCTNNB1TCF7L2 | |
| SCHEMBL2588892 | 0.80 | RAD52 (0.74) | BCHEACHEAPPUSP1WDR48 | |
| SCHEMBL25867340 | 0.78 | APP (0.64) | BCHEACHEAPPCTNNB1TCF7L2 | |
| SCHEMBL25867300 | 0.78 | BCHE (0.71) | BCHEACHEAPPCTNNB1TCF7L2 | |
| SCHEMBL25867456 | 0.77 | APP (0.62) | BCHEACHEAPPCTNNB1TCF7L2 | |
| SCHEMBL25306105 | 0.75 | APP (0.74) | APPUSP1WDR48RAD52KMT2A | |
| SCHEMBL25867222 | 0.74 | APP (0.70) | BCHEACHEAPPCTNNB1TCF7L2 | |
| SCHEMBL4864026 | 0.72 | PDE5A (0.74) | USP1WDR48KMT2AALDH1A1LMNA | |
| SCHEMBL13797314 | 0.71 | MCHR1 (0.65) | BCHEACHEAPPADRA2AMCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023133221-A2 | SMARCA2/4 INHIBITION AS A STRATEGY TO TREAT TUMORS THAT HARBOR ABERRANT BAF ASSEMBLIES | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2023-07-13 | — | — | WO | disclosed |