Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 14/20 | 0.58 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2593998 | 0.93 | NPSR1 (0.63) | NPSR1CNR2CNR1ALDH1A1 | |
| SCHEMBL2587268 | 0.85 | NPSR1 (0.63) | NPSR1PLA2G2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL17278442 | 0.76 | SIGMAR1 (0.62) | SIGMAR1 | |
| SCHEMBL2595693 | 0.75 | NPSR1 (1.00) | NPSR1KDM4EALDH1A1TDP1 | |
| SCHEMBL2594863 | 0.74 | NPSR1 (1.00) | NPSR1SIGMAR1 | |
| SCHEMBL2594864 | 0.74 | NPSR1 (1.00) | NPSR1SIGMAR1 | |
| SCHEMBL15489575 | 0.71 | FABP4 (0.59) | SIGMAR1 | |
| SCHEMBL388824 | 0.69 | MEN1 (0.69) | SIGMAR1KDM4EALDH1A1SMN1; SMN2TDP1 | |
| SCHEMBL15126342 | 0.69 | CNR2 (0.62) | CNR2CNR1SMN1; SMN2 | |
| SCHEMBL2590909 | 0.69 | NPSR1 (1.00) | NPSR1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011137220-A1 | SMALL MOLECULE NEUROPEPTIDE S ANTAGONISTS FOR THE TREATMENT OF ADDICTIVE DISORDERS, MOOD, ANXIETY AND SLEEP DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-11-03 | — | — | WO | disclosed |
| WO-2011137220-A1 | SMALL MOLECULE NEUROPEPTIDE S ANTAGONISTS FOR THE TREATMENT OF ADDICTIVE DISORDERS, MOOD, ANXIETY AND SLEEP DISORDERS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2011-11-03 | — | — | WO | disclosed |