SCHEMBL25868352

SCHEMBL25868352

COC[C@@H]1C[C@@H](NC(=O)Nc2ccc(C)cc2F)C(=O)N1c1ccc(-c2ccccc2P(C)(C)=O)c(F)c1F

nearest known ligand 0.85

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FPR1 P21462 20/20 0.85
FPR2 P25090 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25868800 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL21319192 0.92 FPR1 (1.00) FPR1FPR2
SCHEMBL25868377 0.92 FPR1 (0.84) FPR1FPR2
SCHEMBL21319183 0.91 FPR1 (1.00) FPR1FPR2
SCHEMBL25868380 0.88 FPR1 (0.84) FPR1FPR2
SCHEMBL24093576 0.84 FPR1 (1.00) FPR1FPR2
SCHEMBL21314776 0.84 FPR1 (1.00) FPR1FPR2
SCHEMBL21319424 0.84 FPR1 (1.00) FPR1FPR2
SCHEMBL30832890 0.84 FPR1 (1.00) FPR1FPR2
SCHEMBL21319194 0.82 FPR1 (1.00) FPR1FPR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11708327-B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists BRISTOL-MYERS SQUIBB COMPANY (US) 2023-07-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11708327-B2 Phenylpyrrolidinone formyl peptide 2 receptor agonists FPR1, FPR2, FPR3 FPR1 1/4885FPR2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.