Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 3/20 | 0.60 |
| ▸ | HEXA | P06865 | 6/20 | 0.53 |
| ▸ | HEXB | P07686 | 6/20 | 0.53 |
| ▸ | OGA | O60502 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24796373 | 0.88 | HEXA (0.58) | SIRT1HEXAHEXBOGAALDH1A1 | |
| SCHEMBL30675910 | 0.84 | BRD4 (0.51) | SIRT1BRD4 | |
| SCHEMBL12501840 | 0.83 | MEN1 (0.55) | KDM4EBRD4MEN1KMT2A | |
| SCHEMBL8139824 | 0.83 | BRD4 (0.53) | BRD4HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31655700 | 0.82 | TPSAB1 (0.54) | ALDH1A1BRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL9773851 | 0.82 | TPSAB1 (0.54) | ALDH1A1BRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL22291518 | 0.82 | TPSAB1 (0.54) | ALDH1A1BRD4HDAC3HDAC4HDAC1 | |
| SCHEMBL25974776 | 0.79 | MALT1 (0.52) | ALDH1A1BRD4MEN1KMT2AHDAC3 | |
| SCHEMBL13909963 | 0.79 | SIRT1 (0.94) | SIRT1HEXAHEXBOGAALDH1A1 | |
| Bnipdeta SCHEMBL13909965 | 0.79 | SIRT1 (0.88) | SIRT1HEXAHEXBOGAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373929-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | XIANGBEI WELMAN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230373929-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | XIANGBEI WELMAN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| EP-4215521-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Xiangbei Welman Pharmaceutical Co., Ltd (CN) | 2023-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373929-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | WEE1, CYP51A1, WEE2 | SIRT1 895/4885HEXA 4639/4885HEXB 4682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.