Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 10/20 | 0.54 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 4/20 | 0.52 |
| ▸ | HTR2A | P28223 | 4/20 | 0.52 |
| ▸ | HTR6 | P50406 | 4/20 | 0.52 |
| ▸ | HTR7 | P34969 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12502118 | 0.88 | PABPC1 (0.58) | MEN1KMT2ADRD2DRD3HTR1A | |
| SCHEMBL24796373 | 0.86 | HEXA (0.58) | MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL12413498 | 0.84 | MEN1 (0.64) | MEN1KMT2ADRD2DRD3HTR1A | |
| SCHEMBL25868575 | 0.83 | SIRT1 (0.60) | MEN1KMT2AKDM4EBRD4 | |
| SCHEMBL25974776 | 0.82 | MALT1 (0.52) | MEN1KMT2ADRD2BRD4SIGMAR1 | |
| SCHEMBL20258466 | 0.79 | SIRT1 (0.59) | MEN1KMT2AKDM4EPOLBRXFP1 | |
| SCHEMBL8139824 | 0.79 | BRD4 (0.53) | DRD2BRD4 | |
| SCHEMBL30675910 | 0.78 | BRD4 (0.51) | DRD2BRD4 | |
| SCHEMBL22291518 | 0.78 | TPSAB1 (0.54) | DRD2BRD4 | |
| SCHEMBL31655700 | 0.78 | TPSAB1 (0.54) | DRD2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012104788-A2 | ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-09 | — | — | WO | disclosed |
| WO-2012104788-A2 | ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND USE THEREOF | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2012-08-09 | — | — | WO | disclosed |