Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1B1 | Q16678 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.43 |
| ▸ | USP2 | O75604 | 4/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.41 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.41 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9929137 | 0.81 | HPGD (0.44) | CYP1B1MEN1KMT2AKEAP1NFE2L2 | |
| SCHEMBL1014385 | 0.72 | CA12 (0.54) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL587124 | 0.72 | CES1 (0.54) | MEN1KMT2AUSP2ATMMAPT | |
| SCHEMBL13207607 | 0.71 | HEXA (0.73) | CYP1B1MEN1KMT2AMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9429609 | 0.70 | CA12 (0.52) | MEN1KMT2AALDH1A1SMN1; SMN2HEXA | |
| SCHEMBL17557098 | 0.69 | HEXA (0.59) | MEN1KMT2AKEAP1NFE2L2MAPT | |
| SCHEMBL8547705 | 0.69 | TYMS (0.46) | MEN1KMT2AUSP2ATMMAPT | |
| SCHEMBL19245282 | 0.68 | TERT (0.50) | CYP1B1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL14560580 | 0.66 | CYP1B1 (0.62) | CYP1B1MEN1KMT2AUSP2KEAP1 | |
| SCHEMBL19302158 | 0.66 | TERT (0.56) | CYP1B1MEN1KMT2AUSP2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215521-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Xiangbei Welman Pharmaceutical Co., Ltd (CN) | 2023-07-26 | — | — | EP | disclosed |