Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 4/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CASP1 | P29466 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12179771 | 0.85 | CES1 (0.50) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL8547705 | 0.79 | TYMS (0.46) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL8549161 | 0.78 | CES1 (0.54) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL3183695 | 0.78 | CES1 (0.54) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL12179533 | 0.73 | CES1 (0.49) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL25868685 | 0.72 | CYP1B1 (0.43) | MAPTSMN1; SMN2KDM4EALDH1A1RAB9A | |
| SCHEMBL14922761 | 0.71 | SMN1; SMN2 (0.47) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL14330793 | 0.70 | TTR (0.46) | MAPTSMN1; SMN2PABPC1KDM4EALDH1A1 | |
| SCHEMBL12179578 | 0.70 | CES1 (0.50) | CES1MAPTSMN1; SMN2PABPC1KDM4E | |
| SCHEMBL2156357 | 0.70 | CES1 (1.00) | CES1MAPTSMN1; SMN2PABPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3053914-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2016-08-10 | — | — | EP | disclosed |
| US-20160033521-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2016-02-04 | — | — | US | disclosed |
| US-9115063-B2 | Fluorophore and fluorescent sensor compound containing same | LIGHTSHIP MEDICAL LIMITED (GB) | 2015-08-25 | — | — | US | disclosed |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | LIGHTSHIP MEDICAL LIMITED (GB) | 2012-06-21 | — | — | US | disclosed |
| EP-2417102-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | Glysure Ltd (GB) | 2012-02-15 | — | — | EP | disclosed |
| WO-2010116142-A2 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | GLYSURE LTD (GB) | 2010-10-14 | — | — | WO | disclosed |
| EP-0536208-B1 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | RES CORP TECHNOLOGIES INC (US) | 1998-01-21 | — | — | EP | disclosed |
| US-5635506-A | ANTITUMOR AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1997-06-03 | — | — | US | disclosed |
| EP-0660824-A1 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES (US) | 1995-07-05 | — | — | EP | disclosed |
| WO-1994006771-A9 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | — | 1994-06-09 | — | — | WO | disclosed |
| WO-1994006771-A1 | 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1994-03-31 | — | — | WO | disclosed |
| EP-0536208-A4 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | — | 1993-05-05 | — | — | EP | disclosed |
| EP-0536208-A1 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1993-04-14 | — | — | EP | disclosed |
| WO-1992000281-A1 | 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS | RESEARCH CORPORATION TECHNOLOGIES, INC. (US) | 1992-01-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160033521-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | QRFPR, TRPA1, GPR52 | CES1 2974/4885MAPT 2940/4885SMN1; SMN2 4516/4885 |
| US-20120156793-A1 | FLUOROPHORE AND FLUORESCENT SENSOR COMPOUND CONTAINING SAME | QRFPR, TRPA1, GPR52 | CES1 2930/4885MAPT 2903/4885SMN1; SMN2 4489/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.