Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | CYP1B1 | Q16678 | 10/20 | 0.52 |
| ▸ | TERT | O14746 | 3/20 | 0.50 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868744 | 0.83 | MEN1 (0.45) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL21988071 | 0.81 | POLB (0.59) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL7648035 | 0.81 | POLB (0.59) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL28704128 | 0.79 | CYP1B1 (0.60) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL12869513 | 0.76 | CYP1B1 (0.55) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL3293599 | 0.75 | POLB (0.58) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL1532232 | 0.74 | MAOB (0.73) | HTR1ADRD2HTR2AHTR6MAOB | |
| SCHEMBL3773566 | 0.74 | POLB (0.74) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL30499259 | 0.74 | POLB (0.74) | ALDH1A1POLBKDM4ELMNAMEN1 | |
| SCHEMBL30574144 | 0.74 | TERT (0.65) | ALDH1A1KDM4ELMNAMEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215521-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Xiangbei Welman Pharmaceutical Co., Ltd (CN) | 2023-07-26 | — | — | EP | disclosed |