Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.43 |
| ▸ | HTR1A | P08908 | 3/20 | 0.43 |
| ▸ | BRD4 | O60885 | 3/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | TERT | O14746 | 3/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25868741 | 0.83 | ALDH1A1 (0.55) | MEN1KMT2APOLBKDM4ENPC1 | |
| SCHEMBL12413498 | 0.81 | MEN1 (0.64) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL30149981 | 0.81 | CYP1B1 (0.52) | MEN1KMT2APOLBKDM4ENPC1 | |
| SCHEMBL28942809 | 0.81 | CYP1B1 (0.52) | MEN1KMT2APOLBKDM4ENPC1 | |
| SCHEMBL29391217 | 0.80 | DRD2 (0.56) | MEN1KMT2AKDM4EALDH1A1HTR1A | |
| SCHEMBL17844904 | 0.80 | DRD2 (0.56) | MEN1KMT2AKDM4EALDH1A1HTR1A | |
| SCHEMBL29944565 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2AKDM4EALDH1A1HTR1A | |
| SCHEMBL829637 | 0.78 | ALDH1A1 (0.57) | MEN1KMT2AKDM4EALDH1A1HTR1A | |
| SCHEMBL12263981 | 0.77 | MAOB (0.57) | MEN1KMT2AKDM4EALDH1A1HTR1A | |
| SCHEMBL29263692 | 0.77 | MAOB (0.57) | MEN1KMT2AKDM4EALDH1A1HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230373929-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | XIANGBEI WELMAN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| US-20230373929-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | XIANGBEI WELMAN PHARMACEUTICAL CO., LTD. (CN) | 2023-11-23 | — | — | US | disclosed |
| EP-4215521-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | Xiangbei Welman Pharmaceutical Co., Ltd (CN) | 2023-07-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230373929-A1 | FUSED RING DIIMIDE DERIVATIVE, PREPARATION METHOD AND USE THEREOF | WEE1, CYP51A1, WEE2 | MEN1 1023/4885KMT2A 2753/4885POLB 2066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.