Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK2 | P49760 | 1/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.58 |
| ▸ | NUAK1 | O60285 | 2/20 | 0.53 |
| ▸ | IGF1R | P08069 | 2/20 | 0.53 |
| ▸ | PIM1 | P11309 | 2/20 | 0.53 |
| ▸ | SRC | P12931 | 2/20 | 0.53 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | PLK1 | P53350 | 2/20 | 0.53 |
| ▸ | PKN1 | Q16512 | 2/20 | 0.53 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.53 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21671248 | 0.91 | PTGS1 (0.61) | CLK2PTGS1PTGS2NUAK1IGF1R | |
| SCHEMBL29586871 | 0.84 | PTGS1 (0.59) | CLK2PTGS1PTGS2NUAK1IGF1R | |
| SCHEMBL18096537 | 0.84 | PTGS1 (0.59) | CLK2PTGS1PTGS2NUAK1IGF1R | |
| Noreugenin SCHEMBL29370130 | 0.80 | PTGS2 (0.71) | PTGS1PTGS2NUAK1IGF1RPIM1 | |
| Noreugenin SCHEMBL168822 | 0.80 | PTGS2 (0.71) | PTGS1PTGS2NUAK1IGF1RPIM1 | |
| Alternariol SCHEMBL29423320 | 0.75 | CLK2 (1.00) | CLK2NUAK1IGF1RPIM1SRC | |
| Alternariol SCHEMBL1096830 | 0.75 | CLK2 (1.00) | CLK2NUAK1IGF1RPIM1SRC | |
| SCHEMBL1673012 | 0.73 | PTGS1 (0.62) | PTGS1PTGS2NUAK1IGF1RPIM1 | |
| SCHEMBL15315074 | 0.73 | CYP3A4 (0.58) | CLK2PTGS1PTGS2NUAK1IGF1R | |
| Eugenitol SCHEMBL29881346 | 0.72 | PTGS1 (0.77) | PTGS1PTGS2NUAK1IGF1RPIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230215512-A1 | Systems and Methods for Identifying and Expressing Gene Clusters | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2023-07-06 | — | — | US | disclosed |