Noreugenin

Noreugenin

SCHEMBL168822

Cc1cc(=O)c2c(O)cc(O)cc2o1

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 5/20 0.71
PTGS1 P23219 4/20 0.71
QPCT Q16769 3/20 0.60
CYP3A4 P08684 7/20 0.59
MAPT P10636 7/20 0.59
HSD17B10 Q99714 6/20 0.59
TP53 P04637 6/20 0.59
ALDH1A1 P00352 5/20 0.59
HPGD P15428 5/20 0.59
KDM4E B2RXH2 5/20 0.59
ALOX15 P16050 4/20 0.59
CYP1A2 P05177 4/20 0.59
SMN1; SMN2 Q16637 4/20 0.59
GAA P10253 3/20 0.59
TSHR P16473 3/20 0.59
LMNA P02545 3/20 0.59
RECQL P46063 3/20 0.59
CA9 Q16790 2/20 0.59
POLB P06746 2/20 0.59
CASP1 P29466 1/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Noreugenin SCHEMBL29370130 1.00 PTGS2 (0.71) PTGS2PTGS1QPCTCYP3A4MAPT
SCHEMBL21671248 0.86 PTGS1 (0.61) PTGS2PTGS1QPCTCYP3A4MAPT
SCHEMBL18096537 0.85 PTGS1 (0.59) PTGS2PTGS1QPCTCYP3A4MAPT
SCHEMBL29586871 0.85 PTGS1 (0.59) PTGS2PTGS1QPCTCYP3A4MAPT
SCHEMBL1673012 0.84 PTGS1 (0.62) PTGS2PTGS1QPCTCYP3A4MAPT
Eugenin SCHEMBL1860860 0.83 PTGS1 (1.00) PTGS2PTGS1CYP3A4MAPTHSD17B10
Eugenin SCHEMBL29373728 0.83 PTGS1 (1.00) PTGS2PTGS1CYP3A4MAPTHSD17B10
SCHEMBL22738310 0.81 MEN1 (0.75) PTGS2PTGS1QPCTCYP3A4MAPT
SCHEMBL25868821 0.80 CLK2 (0.60) PTGS2PTGS1QPCTCYP3A4MAPT
SCHEMBL13532121 0.80 PTGS1 (0.59) PTGS2PTGS1QPCTCYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 303 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240102068-A1 C-GLYCOSYLTRANSFERASE VARIANTS AND USE THEREOF KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2024-03-28 US claimed
CN-117425727-A Variants of C-glucosyltransferase and uses thereof 韩国科学技术院 2024-01-19 CN claimed
EP-4286515-A1 C-GLYCOSYLTRANSFERASE VARIANTS AND USE THEREOF Korea Advanced Institute of Science and Technology (KR) 2023-12-06 EP claimed
WO-2022164226-A1 C-GLYCOSYLTRANSFERASE VARIANTS AND USE THEREOF 한국과학기술원 2022-08-04 WO claimed
CN-114392260-A Medicine for relieving anxiety and depression 重庆市九龙坡区精神卫生中心(重庆市九龙坡区石坪桥医院) 2022-04-26 CN claimed
US-20210244635-A1 ENZYMATIC MOLECULE MIMICKING ANTI-OXIDANT ACTIVITY BIONUCLEI (FR) 2021-08-12 US claimed
CN-112969782-A Method for providing malonyl-coenzyme A in coryneform bacteria and for producing polyphenols and polyketones by means of coryneform bacteria 于利奇研究中心有限公司 2021-06-15 CN claimed
EP-3801058-A1 ENZYMATIC MOLECULE MIMICKING ANTI-OXIDANT ACTIVITY Bionuclei (FR) 2021-04-14 EP claimed
CN-110896642-A Novel malonyl-CoA biosensor based on type III polyketide synthase and use thereof 韩国科学技术院 2020-03-20 CN claimed
EP-3608417-A1 NOVEL MALONYL-COA BIOSENSOR BASED ON TYPE III POLYKETIDE SYNTHASE, AND USE THEREOF Korea Advanced Institute of Science and Technology (KR) 2020-02-12 EP claimed
CN-104230868-B A kind of chemical preparation process of compound 2-methyl-5,7-dihydroxyl chromone SYNYOO NEW MATERIALS CO., LTD. (CN) 2016-04-27 CN claimed
CN-104230868-A Chemical preparation method of compound 2-methyl-5,7-dihydroxy chromone GUANGDONG SYNYOO NEW MATERIALS COMPANY LTD 2014-12-24 CN claimed
JP-2255672-A None JP disclosed
JP-1031719-A None JP disclosed
EP-3592329-B1 USE OF COMPATIBLE SOLUTES SUSONITY Commercial GmbH (DE) 2026-02-18 EP disclosed
EP-4007561-B1 PREVENTION AND REDUCTION OF CORNIFICATION DISORDERS AND RELATED COSMETIC AGENTS MERCK PATENT GMBH (DE) 2025-08-27 EP disclosed
US-20050043398-A1 Use of chromen-4-one derivatives MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) 2005-02-24 US disclosed
EP-1508327-A1 Use of chromen-4-one derivatives for the care of skin and hair MERCK PATENT GmbH (DE) 2005-02-23 EP disclosed
JP-H02255672-A NEW CHROMONE DERIVATIVE AND ANTIALLERGIC AGENT COMPRISING SAME DERIVATIVE AS ACTIVE INGREDIENT TSUMURA & CO 1990-10-16 JP disclosed
JP-S6431719-A ANTIALLERGIC AGENT TSUMURA & CO 1989-02-02 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050043398-A1 Use of chromen-4-one derivatives CYP8B1, CYP7B1, CYP2R1 PTGS2 4084/4885PTGS1 3548/4885QPCT 2486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.