⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24689778 | 0.80 | — | — | |
| SCHEMBL8011007 | 0.76 | — | — | |
| SCHEMBL8011000 | 0.74 | — | — | |
| SCHEMBL8008229 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL8008227 | 0.71 | ALDH1A1 (0.34) | — | |
| SCHEMBL5655389 | 0.69 | ADORA2A (0.38) | — | |
| SCHEMBL11101297 | 0.67 | FGFR1 (0.47) | — | |
| SCHEMBL3585680 | 0.67 | CSNK2A2 (0.46) | — | |
| SCHEMBL11047604 | 0.66 | HCAR1 (0.45) | — | |
| SCHEMBL3584041 | 0.65 | SMN1; SMN2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-13 | — | — | US | disclosed |