⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12344479 | 0.79 | — | — | |
| SCHEMBL17689166 | 0.77 | — | — | |
| SCHEMBL12569981 | 0.77 | ALDH1A1 (0.32) | — | |
| SCHEMBL8011000 | 0.76 | — | — | |
| SCHEMBL859688 | 0.76 | — | — | |
| SCHEMBL22125858 | 0.76 | — | — | |
| SCHEMBL25868933 | 0.76 | — | — | |
| SCHEMBL5655389 | 0.75 | ADORA2A (0.38) | — | |
| SCHEMBL21486293 | 0.74 | APOBEC3A (0.33) | — | |
| SCHEMBL13384272 | 0.74 | KDM4E (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230219970-A1 | DIHYDROCHROMENE DERIVATIVES | Sumitomo Pharma Co., Ltd. (JP) | 2023-07-13 | — | — | US | disclosed |
| US-11639357-B2 | Dihydrochromene derivatives | Sumitomo Pharma Co., Ltd. (JP) | 2023-05-02 | — | — | US | disclosed |
| US-20210002290-A1 | DIHYDROCHROMENE DERIVATIVES | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2021-01-07 | — | — | US | disclosed |
| US-10807993-B2 | Dihydrochromene derivatives | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-10-20 | — | — | US | disclosed |
| US-20200216461-A1 | DIHYDROCHROMENE DERIVATIVE | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2020-07-09 | — | — | US | disclosed |
| US-9315521-B2 | Pyrimidines as novel therapeutic agents | UNIVERSITé LAVAL (CA) | 2016-04-19 | — | — | US | disclosed |
| US-9315521-B2 | Pyrimidines as novel therapeutic agents | UNIVERSITé LAVAL (CA) | 2016-04-19 | — | — | US | disclosed |
| US-6107312-A | BACTERICIDE | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 2000-08-22 | — | — | US | disclosed |
| EP-0683776-B1 | SUBSTITUTED HETEROARYLALKYLTHIOPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEM FAB (DE) | 1999-04-07 | — | — | EP | disclosed |
| US-5587389-A | Substituted heteroarylaklylthiopyridines for controlling helicobacter bacteria | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-12-24 | — | — | US | disclosed |
| WO-1996000224-A1 | 4-S- AND N-SUBSTITUTED 6-ALKYLPYRIDINES FOR CONTROLLING HELICOBACTER BACTERIA | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1996-01-04 | — | — | WO | disclosed |
| US-4292431-A | Process for the production of hydroxymethylimidazoles | KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 1981-09-29 | — | — | US | disclosed |