Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30235112 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL30380933 | 0.88 | RIPK1 (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL31054488 | 0.86 | CYP2C19 (0.42) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL23991738 | 0.85 | KMT2A (0.45) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL23883802 | 0.84 | ALDH1A1 (0.34) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL22032917 | 0.84 | GAA (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL29439764 | 0.84 | GAA (0.40) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL31162358 | 0.82 | ALDH1A1 (0.33) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL22716072 | 0.82 | CYP2C19 (0.49) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA | |
| SCHEMBL22715137 | 0.82 | CYP2C19 (0.53) | ALDH1A1CYP1A2CYP2C9CYP2C19GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023135107-A1 | PYRIDAZINYL AMINO DERIVATIVES AS ALK5 INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-07-20 | — | — | WO | disclosed |