SCHEMBL29439764

SCHEMBL29439764

O=C(ON1C(=O)c2ccccc2C1=O)C1CCOCC1

nearest known ligand 0.40

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.40
KMT2A Q03164 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
CYP2C19 P33261 2/20 0.39
ALDH1A1 P00352 5/20 0.38
LMNA P02545 4/20 0.38
CYP1A2 P05177 2/20 0.38
CYP2C9 P11712 2/20 0.38
MAPT P10636 2/20 0.38
RIPK1 Q13546 1/20 0.37
CNR1 P21554 1/20 0.36
CNR2 P34972 1/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22032917 1.00 GAA (0.40) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL30380933 0.91 RIPK1 (0.40) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL23991738 0.89 KMT2A (0.45) GAAKMT2ACYP2C19ALDH1A1LMNA
SCHEMBL22716072 0.86 CYP2C19 (0.49) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL22715137 0.86 CYP2C19 (0.53) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL13479740 0.84 CYP2C19 (0.55) KMT2ASMN1; SMN2CYP2C19ALDH1A1LMNA
SCHEMBL25869168 0.84 ALDH1A1 (0.40) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL31054488 0.83 CYP2C19 (0.42) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL25869112 0.83 RIPK1 (0.36) GAAKMT2ASMN1; SMN2CYP2C19ALDH1A1
SCHEMBL30351147 0.82 ALDH1A1 (0.39) KMT2ASMN1; SMN2CYP2C19ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4676476-A1 INHIBITORS OF TDP-43 AND TAU AGGREGATION Aquinnah Pharmaceuticals, Inc. (US) 2026-01-14 EP disclosed
EP-4665454-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF Dice Alpha, Inc. (US) 2025-12-24 EP disclosed
CN-119731159-A SARS-CoV2 main proteinase inhibitor 吉利德科学公司 2025-03-28 CN disclosed
WO-2025049994-A1 COMPOUNDS AND COMPOSITIONS AS CBP/P300 DEGRADERS AND USES THEREOF ONCOPIA THERAPEUTICS, INC. D/B/A SK LIFE SCIENCE LABS (US) 2025-03-06 WO disclosed
CN-118908957-A Small molecule inhibitors of NF- κB induced kinase 詹森药业有限公司 2024-11-08 CN disclosed
WO-2024187126-A1 INHIBITORS OF TDP-43 AND TAU AGGREGATION AQUINNAH PHARMACEUTICALS, INC. (US) 2024-09-12 WO disclosed
WO-2024173173-A1 IMIDAZOTRIAZINE IL-17A MODULATORS AND USES THEREOF DICE ALPHA, INC. (US) 2024-08-22 WO disclosed
CN-114222737-B Small molecule inhibitors of NF- κB induced kinase 詹森药业有限公司 2024-07-26 CN disclosed
EP-3976597-A1 SMALL MOLECULE INHIBITORS OF NF-KB INDUCING KINASE Janssen Pharmaceutica NV (BE) 2022-04-06 EP disclosed