Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.76 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.76 |
| ▸ | THRB | P10828 | 1/20 | 0.76 |
| ▸ | RECQL | P46063 | 1/20 | 0.76 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.76 |
| ▸ | RARB | P10826 | 14/20 | 0.63 |
| ▸ | RARG | P13631 | 14/20 | 0.63 |
| ▸ | RARA | P10276 | 13/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | TP53 | P04637 | 1/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.63 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL444659 | 0.86 | RARG (0.76) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL173380 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL29359220 | 0.86 | MEN1 (1.00) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL8900666 | 0.85 | RARB (0.78) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7926641 | 0.84 | MEN1 (0.70) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL8439716 | 0.83 | MEN1 (0.69) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL9010769 | 0.82 | MEN1 (0.71) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7926644 | 0.81 | MEN1 (0.70) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7920626 | 0.81 | MEN1 (0.66) | MEN1KMT2ATHRBRECQLNR2E1 | |
| SCHEMBL7920630 | 0.80 | RARG (0.79) | MEN1KMT2ATHRBRECQLNR2E1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11707442-B2 | Antibacterial and antifungal compounds | THE GENERAL HOSPITAL CORPORATION (US) | 2023-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707442-B2 | Antibacterial and antifungal compounds | RXRA, VDR, RXRB | MEN1 3858/4885KMT2A 3841/4885THRB 1760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.