Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.38 |
| ▸ | MEN1 | O00255 | 9/20 | 0.38 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18863392 | 0.93 | MAPT (0.33) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL18863388 | 0.92 | KDM4E (0.31) | KMT2AMEN1ALDH1A1KDM4ETSHR | |
| SCHEMBL28705799 | 0.87 | KDM4E (0.31) | ALDH1A1KDM4ETSHRSIGMAR1 | |
| SCHEMBL28932832 | 0.87 | ALDH1A1 (0.31) | MAPTALDH1A1GAAHSD17B10KDM4E | |
| SCHEMBL25870678 | 0.86 | MAPT (0.40) | KMT2AMEN1MAPTALDH1A1USP2 | |
| SCHEMBL25870682 | 0.86 | NOX4 (0.32) | KMT2AMEN1MAPTALDH1A1RAB9A | |
| SCHEMBL25870726 | 0.86 | LMNA (0.34) | KMT2AMEN1MAPTRAB9AGAA | |
| SCHEMBL17765782 | 0.86 | KDM4E (0.34) | KMT2AMEN1MAPTALDH1A1USP2 | |
| SCHEMBL17765779 | 0.86 | KDM4E (0.34) | KMT2AMEN1MAPTALDH1A1USP2 | |
| SCHEMBL25870705 | 0.85 | MAPT (0.32) | KMT2AMEN1MAPTALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |