SCHEMBL25870774

SCHEMBL25870774

O=C1C(=Cc2ccc(N(c3ccccc3)c3cc4ccccc4s3)[se]2)C(=O)c2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.32
HPGD P15428 2/20 0.32
KMT2A Q03164 2/20 0.32
MAPT P10636 1/20 0.32
THRB P10828 1/20 0.32
RECQL P46063 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
GSK3B P49841 1/20 0.31
HTT P42858 1/20 0.31
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA4 P22748 1/20 0.30
CA5A P35218 1/20 0.30
CA7 P43166 1/20 0.30
CA9 Q16790 1/20 0.30
CA14 Q9ULX7 1/20 0.30
CA5B Q9Y2D0 1/20 0.30
CYP2A6 P11509 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25870812 0.95 GSK3B (0.31) GSK3B
SCHEMBL25870773 0.80 ALDH1A1 (0.45) ALDH1A1HPGDKMT2AMAPTTHRB
SCHEMBL25870797 0.79 LCK (0.34) ALDH1A1HPGDKMT2AMAPTTDP1
SCHEMBL18913102 0.79 ALDH1A1 (0.45) ALDH1A1HPGDKMT2AMAPTTHRB
SCHEMBL25870801 0.77 LCK (0.33) ALDH1A1HPGDKMT2AMAPTNPSR1
SCHEMBL17765829 0.76 PTPN1 (0.35) ALDH1A1HPGDKMT2AMAPTNPSR1
SCHEMBL29993362 0.76 PTPN1 (0.35) ALDH1A1HPGDKMT2AMAPTNPSR1
SCHEMBL25870782 0.76 MAPT (0.36) ALDH1A1HPGDKMT2AMAPTTHRB
SCHEMBL12761288 0.75 LCK (0.45) ALDH1A1HPGDKMT2AMAPTTHRB
SCHEMBL18913233 0.73 ALDH1A1 (0.39) ALDH1A1HPGDKMT2AMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711930-B2 2023-07-25 US disclosed