Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870774 | 0.80 | ALDH1A1 (0.32) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL10134166 | 0.79 | KMT2A (0.50) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL10134160 | 0.76 | KMT2A (0.53) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL18913100 | 0.76 | ALDH1A1 (0.54) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL25870797 | 0.75 | LCK (0.34) | ALDH1A1KMT2AHPGDMAPTMEN1 | |
| SCHEMBL17765829 | 0.75 | PTPN1 (0.35) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL29993362 | 0.75 | PTPN1 (0.35) | ALDH1A1KMT2AHPGDHTTMAPT | |
| SCHEMBL25870775 | 0.74 | USP8 (0.33) | KMT2AMEN1PKM | |
| SCHEMBL25870812 | 0.74 | GSK3B (0.31) | — | |
| SCHEMBL25870801 | 0.74 | LCK (0.33) | ALDH1A1KMT2AHPGDMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |