Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.36 |
| ▸ | PKM | P14618 | 3/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.33 |
| ▸ | HTT | P42858 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870777 | 0.89 | PTPN1 (0.32) | MAPTKMT2APKMUSP2 | |
| SCHEMBL25870797 | 0.78 | LCK (0.34) | MAPTKMT2APKMUSP2LCK | |
| SCHEMBL25870810 | 0.78 | MAOB (0.32) | KMT2APKMMEN1MAOB | |
| SCHEMBL25870779 | 0.77 | PTPN1 (0.38) | MAPTKMT2APKMLCKL3MBTL1 | |
| SCHEMBL12761710 | 0.77 | LCK (0.51) | MAPTKMT2APKMUSP2LCK | |
| SCHEMBL25870801 | 0.76 | LCK (0.33) | MAPTKMT2APKMUSP2LCK | |
| SCHEMBL17765829 | 0.76 | PTPN1 (0.35) | MAPTKMT2AL3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL25870774 | 0.76 | ALDH1A1 (0.32) | MAPTKMT2AALDH1A1HTTHPGD | |
| SCHEMBL25870828 | 0.75 | MAPT (0.32) | MAPTKMT2APKMUSP2L3MBTL1 | |
| SCHEMBL17765710 | 0.74 | SIGMAR1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11711930-B2 | — | — | 2023-07-25 | — | — | US | disclosed |