SCHEMBL25870775

SCHEMBL25870775

N#Cc1ccccc1N(c1ccccc1)c1ccc(C=C2C(=O)c3ccccc3C2=O)[se]1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
USP8 P40818 1/20 0.33
USP7 Q93009 1/20 0.33
MEN1 O00255 1/20 0.33
PKM P14618 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25870811 0.91 CA1 (0.31) USP8USP7
SCHEMBL17765829 0.81 PTPN1 (0.35) MEN1KMT2A
SCHEMBL29993362 0.81 PTPN1 (0.35) MEN1KMT2A
SCHEMBL25870789 0.79 CA1 (0.33) MEN1PKMKMT2A
SCHEMBL25870788 0.77 CA1 (0.34) MEN1PKMKMT2A
SCHEMBL25870801 0.76 LCK (0.33) MEN1PKMKMT2A
SCHEMBL25870791 0.75 MEN1 (0.33) MEN1PKMKMT2A
SCHEMBL18913101 0.75 KMT2A (0.44) USP8USP7MEN1PKMKMT2A
SCHEMBL25870773 0.74 ALDH1A1 (0.45) MEN1PKMKMT2A
SCHEMBL17765710 0.74 SIGMAR1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11711930-B2 2023-07-25 US disclosed