Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
| ▸ | MDH1 | P40925 | 4/20 | 0.36 |
| ▸ | MDH2 | P40926 | 4/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.35 |
| ▸ | ESR1 | P03372 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8352192 | 0.93 | SHBG (0.50) | SHBGCYP3A4SMN1; SMN2TAAR1SLC6A2 | |
| SCHEMBL23221272 | 0.86 | SHBG (0.45) | SHBGCYP3A4SMN1; SMN2TAAR1MAPT | |
| SCHEMBL14685623 | 0.84 | TSHR (0.48) | SHBGCYP3A4SMN1; SMN2TAAR1SLC6A2 | |
| SCHEMBL19026593 | 0.82 | SHBG (0.69) | SHBGCYP3A4SMN1; SMN2SLC6A2SLC6A4 | |
| SCHEMBL19033678 | 0.81 | TAAR1 (0.60) | SHBGCYP3A4HIF1ACYP2D6TAAR1 | |
| SCHEMBL6550540 | 0.81 | SHBG (0.61) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL21862602 | 0.80 | SHBG (0.41) | SHBGSMN1; SMN2TAAR1SLC6A2MAPT | |
| SCHEMBL10515698 | 0.80 | SHBG (0.67) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL14685562 | 0.79 | CYP2D6 (0.40) | SHBGCYP3A4SMN1; SMN2HIF1ACYP2D6 | |
| SCHEMBL22631906 | 0.79 | SHBG (0.39) | SHBGCYP3A4SMN1; SMN2CYP2D6TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023136342-A1 | TSP1 INHIBITOR | 第一三共株式会社 | 2023-07-20 | — | — | WO | disclosed |