Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 17/20 | 0.66 |
| ▸ | EGFR | P00533 | 3/20 | 0.61 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25869799 | 0.94 | ALK (0.75) | ALKEGFRZAP70 | |
| SCHEMBL30497500 | 0.90 | EGFR (0.65) | ALKEGFRZAP70 | |
| SCHEMBL26500041 | 0.90 | EGFR (0.65) | ALKEGFRZAP70 | |
| SCHEMBL25869936 | 0.90 | EGFR (0.76) | ALKEGFRZAP70 | |
| SCHEMBL25871546 | 0.88 | ALK (0.64) | ALKEGFRZAP70 | |
| SCHEMBL25872847 | 0.87 | ALK (0.63) | ALKEGFRZAP70 | |
| SCHEMBL25872148 | 0.87 | ALK (0.73) | ALKEGFR | |
| SCHEMBL25872232 | 0.87 | ALK (0.59) | ALKEGFR | |
| SCHEMBL30497488 | 0.84 | ALK (0.74) | ALKEGFRZAP70 | |
| SCHEMBL29059678 | 0.84 | ALK (0.74) | ALKEGFRZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4212522-A1 | COMPOUNDS FOR SUPPRESSING EGFR MUTANT CANCER AND PHARMACEUTICAL USE THEREOF | J2H Biotech Inc. (KR) | 2023-07-19 | — | — | EP | disclosed |