Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12210618 | 0.87 | POLB (0.61) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4940110 | 0.82 | LMNA (0.60) | POLBALDH1A1SMN1; SMN2PKMLMNA | |
| SCHEMBL10089746 | 0.80 | LMNA (0.65) | POLBALDH1A1SMN1; SMN2PKMHSD17B10 | |
| SCHEMBL6141396 | 0.80 | POLB (0.68) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL30181739 | 0.79 | SMN1; SMN2 (0.57) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL202298 | 0.79 | SMN1; SMN2 (0.57) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL14612413 | 0.78 | POLB (0.66) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL84337 | 0.78 | POLB (0.66) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3524765 | 0.78 | POLB (0.66) | POLBALDH1A1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4942304 | 0.78 | TPSAB1 (0.54) | POLBALDH1A1PKMHSD17B10LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3395795-B1 | MALONONITRILE OXIME ETHER COMPOUND AND USE THEREOF | SHENYANG SINOCHEM AGROCHEMICALS R & D CO LTD (CN) | 2023-07-19 | — | — | EP | disclosed |