Biphenyl

Biphenyl

SCHEMBL2587427

C=CC(=O)OCCOCCO.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.59
TSHR P16473 5/20 0.59
TP53 P04637 2/20 0.59
HIF1A Q16665 2/20 0.59
HSD17B10 Q99714 1/20 0.59
THRB P10828 2/20 0.58
CYP3A4 P08684 1/20 0.42
USP2 O75604 1/20 0.40
HCAR2 Q8TDS4 1/20 0.40
HPGD P15428 1/20 0.39
KMT2A Q03164 2/20 0.38
PTK2B Q14289 1/20 0.38
RECQL P46063 1/20 0.38
AKR1B10 O60218 1/20 0.38
AKR1B1 P15121 1/20 0.38
KDM4E B2RXH2 1/20 0.37
GAA P10253 1/20 0.37
TARBP2 Q15633 1/20 0.36
MEN1 O00255 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL14674230 0.90 THRB (0.65) ALDH1A1TSHRTP53HIF1AHSD17B10
Phenol SCHEMBL20484935 0.89 TSHR (0.58) ALDH1A1TSHRTP53HIF1AHSD17B10
Phthalic Acid SCHEMBL28239002 0.88 ALDH1A1 (0.56) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL1537388 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL10533428 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL10530471 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL8852469 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL1537378 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL130139 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10
SCHEMBL139735 0.85 TSHR (0.83) ALDH1A1TSHRTP53HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8765310-B2 Nonaqueous electrolytic solution and nonaqueous electrolyte secondary battery using the same HITACHI, LTD. (JP) 2014-07-01 US disclosed
US-20110269026-A1 NONAQUEOUS ELECTROLYTIC SOLUTION AND NONAQUEOUS ELECTROLYTE SECONDARY BATTERY USING THE SAME HITACHI, LTD. (JP) 2011-11-03 US disclosed