SCHEMBL25874452

SCHEMBL25874452

Cc1ccc(P)c(-n2nnc3ccccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNMA1 Q12791 1/20 0.50
SMN1; SMN2 Q16637 3/20 0.47
TSHR P16473 2/20 0.47
ALDH1A1 P00352 2/20 0.46
GAA P10253 2/20 0.46
SLC9A1 P19634 3/20 0.44
RAB9A P51151 1/20 0.43
KMT2A Q03164 2/20 0.42
KEAP1 Q14145 1/20 0.42
MGAM O43451 1/20 0.42
AMY1A P0DUB6 1/20 0.42
SI P14410 1/20 0.42
MGAM2 Q2M2H8 1/20 0.42
MEN1 O00255 1/20 0.42
POLB P06746 3/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41
RECQL P46063 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HSD17B10 Q99714 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13772814 0.84 KCNMA1 (0.57) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL890612 0.82 KCNMA1 (0.67) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL25873809 0.82 KCNMA1 (0.50) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL29845601 0.82 KCNMA1 (0.67) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL24222175 0.82 KCNMA1 (0.50) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL24060749 0.81 KCNMA1 (0.53) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL26035802 0.79 KCNMA1 (0.48) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL13772823 0.79 KCNMA1 (0.50) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL25873798 0.79 KCNMA1 (0.50) KCNMA1SMN1; SMN2TSHRALDH1A1GAA
SCHEMBL8645601 0.79 KCNMA1 (0.67) KCNMA1SMN1; SMN2TSHRALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4212519-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LT Materials Co., Ltd. (KR) 2023-07-19 EP disclosed