Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | SLC6A9 | P48067 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25875393 | 0.89 | OPRL1 (0.40) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25874982 | 0.88 | OPRM1 (0.45) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25875253 | 0.85 | CYP2D6 (0.46) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25875252 | 0.85 | CYP2D6 (0.46) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL21104902 | 0.85 | CYP2D6 (0.46) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25311909 | 0.85 | OPRL1 (0.42) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL19851188 | 0.85 | OPRD1 (0.43) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25312897 | 0.82 | RAB9A (0.42) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25310611 | 0.82 | CRBN (0.40) | OPRL1OPRD1OPRM1OPRK1SLC6A9 | |
| SCHEMBL25875273 | 0.82 | RAB9A (0.42) | OPRL1OPRD1OPRM1OPRK1SLC6A9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230210851-A1 | SPIRO-LACTAM COMPOUNDS AND METHODS OF TREATING VIRAL INFECTIONS USING THE SAME | APTINYX INC (US) | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230210851-A1 | SPIRO-LACTAM COMPOUNDS AND METHODS OF TREATING VIRAL INFECTIONS USING THE SAME | ACE, ACE2, PREP | OPRL1 1783/4885OPRD1 2074/4885OPRM1 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.