SCHEMBL25875300

SCHEMBL25875300

C=CC(=O)Oc1ccc(-c2ccc3c(oc4c(F)c(OC(=O)C=C)ccc43)c2C)cc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.35
MEN1 O00255 2/20 0.35
THRB P10828 2/20 0.35
HTT P42858 2/20 0.35
GAA P10253 2/20 0.35
ADORA3 P0DMS8 1/20 0.35
TYMS P04818 1/20 0.34
POLB P06746 2/20 0.34
KDM4E B2RXH2 4/20 0.32
HPGD P15428 3/20 0.32
ALDH1A1 P00352 2/20 0.32
HSD17B10 Q99714 2/20 0.32
TSHR P16473 1/20 0.32
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32
LMNA P02545 2/20 0.31
PSMD14 O00487 1/20 0.31
MMP2 P08253 1/20 0.31
BLM P54132 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875553 0.91 KMT2A (0.39) KMT2AMEN1THRBHTTGAA
SCHEMBL25875664 0.91 KMT2A (0.41) KMT2AMEN1THRBHTTGAA
SCHEMBL25875376 0.87 ADORA3 (0.36) KMT2AMEN1THRBHTTGAA
SCHEMBL25876388 0.86 KMT2A (0.34) KMT2AMEN1THRBHTTGAA
SCHEMBL25873932 0.86 HPGD (0.40) KMT2ATHRBHTTGAATYMS
SCHEMBL25875988 0.86 ALDH1A1 (0.39) KMT2AMEN1THRBHTTGAA
SCHEMBL25875380 0.85 TYMS (0.33) THRBADORA3TYMS
SCHEMBL25875301 0.84 KMT2A (0.37) KMT2AMEN1HTTGAAADORA3
SCHEMBL25876706 0.84 ADORA3 (0.36) KMT2AMEN1THRBHTTGAA
SCHEMBL25875451 0.83 ABL1 (0.33) THRBADORA3TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed