SCHEMBL25875382

SCHEMBL25875382

C=C(C)C(=O)Oc1ccc(-c2ccc3c(oc4c(F)c(OC(=O)C(=C)C)ccc43)c2C(F)(F)F)cc1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.35
KMT2A Q03164 2/20 0.33
ADORA3 P0DMS8 1/20 0.33
ATM Q13315 1/20 0.33
BACE1 P56817 1/20 0.30
MEN1 O00255 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25876563 0.93 ELANE (0.37) ELANEKMT2AADORA3ATMBACE1
SCHEMBL25876384 0.92 ELANE (0.35) ELANEKMT2AADORA3ATMBACE1
SCHEMBL25875782 0.90 KMT2A (0.38) ELANEKMT2AADORA3ATMMEN1
SCHEMBL25876151 0.88 ADORA3 (0.36) ELANEKMT2AADORA3ATMBACE1
SCHEMBL25876794 0.87 ADORA3 (0.36) ELANEKMT2AADORA3ATM
SCHEMBL25875301 0.86 KMT2A (0.37) ELANEKMT2AADORA3ATMMEN1
SCHEMBL25875452 0.86 ADORA3 (0.34) ELANEKMT2AADORA3ATM
SCHEMBL25874024 0.85 SLC26A3 (0.34) ELANE
SCHEMBL25876472 0.85 KMT2A (0.36) ELANEKMT2AADORA3ATMBACE1
SCHEMBL25875377 0.84 MAOA (0.36) ELANEKMT2AADORA3ATMBACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed