SCHEMBL25875490

SCHEMBL25875490

CC(F)(F)C(F)(F)Oc1cccc(Br)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 8/20 0.41
CYP1A2 P05177 2/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
ALDH1A1 P00352 2/20 0.38
MAPK1 P28482 1/20 0.38
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
RECQL P46063 1/20 0.36
KDM4E B2RXH2 1/20 0.36
LMNA P02545 1/20 0.36
DDR1 Q08345 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA5A P35218 1/20 0.35
CA9 Q16790 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14157395 0.85 MAOB (0.43) MAOBCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL11720083 0.85 MAOB (0.43) MAOBCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL4875079 0.85 MAOB (0.43) MAOBCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL25875527 0.80 PGR (0.31)
SCHEMBL31275767 0.80 MAOB (0.46) MAOBCYP1A2ALDH1A1MAPK1GAA
SCHEMBL29351368 0.80 MAOB (0.46) MAOBALDH1A1GAAMAPTDDR1
SCHEMBL4194354 0.80 MAOB (0.46) MAOBCYP1A2ALDH1A1MAPK1GAA
SCHEMBL278324 0.80 MAOB (0.46) MAOBALDH1A1GAAMAPTDDR1
SCHEMBL11721758 0.80 MAOB (0.40) MAOBCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL25875492 0.79 ACHE (0.50) NPSR1ALDH1A1MAPK1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed