SCHEMBL25875519

SCHEMBL25875519

CC(F)(F)C(F)(F)OCc1ccc(Br)cc1

nearest known ligand 0.45

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.45
LMNA P02545 2/20 0.38
APP P05067 1/20 0.38
MAOB P27338 5/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
HTT P42858 1/20 0.37
MAOA P21397 2/20 0.36
L3MBTL1 Q9Y468 2/20 0.35
TDP1 Q9NUW8 1/20 0.35
TAAR1 Q96RJ0 2/20 0.34
RXRA P19793 1/20 0.34
RXRB P28702 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
HPGD P15428 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11957478 0.79 IDO1 (0.52) IDO1LMNAAPPMAOBNPC1
SCHEMBL21824144 0.79 IDO1 (0.52) IDO1APPMAOBNPC1RAB9A
SCHEMBL1567600 0.74 IDO1 (0.47) IDO1LMNAAPPMAOBNPC1
SCHEMBL19485039 0.74 KMT2A (0.35) MAOBRXRARXRBALDH1A1
SCHEMBL2215266 0.70 RXRA (0.46) IDO1LMNAMAOBMAOARXRA
SCHEMBL7622837 0.69 IDO1 (0.45) IDO1APPMAOBNPC1RAB9A
SCHEMBL3681250 0.69 IDO1 (0.41) IDO1LMNAMAOBNPC1RAB9A
SCHEMBL16685648 0.69 ESR1 (0.43) IDO1LMNATAAR1ALDH1A1
SCHEMBL18492177 0.69 TAAR1 (0.40) IDO1LMNATAAR1ALDH1A1
SCHEMBL23454355 0.68 ALDH1A1 (0.58) IDO1APPMAOBALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814463-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-11-14 US disclosed
WO-2023157862-A1 METHOD FOR PRODUCING FLUOROETHER ダイキン工業株式会社 2023-08-24 WO disclosed
US-20230227604-A1 FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2023-07-20 US disclosed
US-11643500-B2 Fluorinated aromatic polymer and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2023-05-09 US disclosed