Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.46 |
| ▸ | RXRB | P28702 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 4/20 | 0.46 |
| ▸ | PPARD | Q03181 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 3/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | SLC16A3 | O15427 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.43 |
| ▸ | MCTS1 | Q9ULC4 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL883026 | 0.83 | SLC16A3 (0.55) | PPARAPPARDPPARGSLC16A3SLC16A1 | |
| SCHEMBL13994548 | 0.83 | KMT2A (0.50) | RXRARXRBMAOBLMNAIDO1 | |
| SCHEMBL2352150 | 0.82 | RXRA (0.46) | RXRARXRBPPARAPPARDPPARG | |
| SCHEMBL8935661 | 0.82 | SLC16A3 (0.46) | PPARAMAOBPPARGSLC16A3SLC16A1 | |
| SCHEMBL11121410 | 0.81 | RXRA (0.46) | RXRARXRBMAOBFFAR1FFAR4 | |
| SCHEMBL31377393 | 0.81 | NPC1 (0.53) | PPARAPPARDPPARGFFAR1SLC16A3 | |
| SCHEMBL2221138 | 0.81 | SLC16A3 (0.53) | PPARGSLC16A3LMNASLC16A1MCTS1 | |
| SCHEMBL8935846 | 0.79 | PPARA (0.50) | PPARAPPARDMAOBPPARGFFAR1 | |
| SCHEMBL2218889 | 0.79 | KMT2A (0.41) | RXRARXRBMAOBFFAR1FFAR4 | |
| Clobuzarit SCHEMBL187456 | 0.78 | SLC16A3 (0.62) | PPARAPPARGSLC16A3SLC16A1MCTS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4482571-A | BENZYLOXY ACIDS | UNIVERSITY OF PITTSBURGH (US) | 1984-11-13 | — | — | US | claimed |
| US-8722686-B2 | Hydroxamic acid derivatives useful as antibacterial agents | PFIZER INC. (US) | 2014-05-13 | — | — | US | disclosed |
| US-20110178042-A1 | Hydroxamic Acid Derivatives Useful as Antibacterial Agents | PFIZER INC. (US) | 2011-07-21 | — | — | US | disclosed |
| US-4482571-A | BENZYLOXY ACIDS | UNIVERSITY OF PITTSBURGH (US) | 1984-11-13 | — | — | US | disclosed |
| US-4482571-A | BENZYLOXY ACIDS | UNIVERSITY OF PITTSBURGH (US) | 1984-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178042-A1 | Hydroxamic Acid Derivatives Useful as Antibacterial Agents | HCAR1, HDAC1, H1-0 | RXRA 823/4885RXRB 1017/4885PPARA 1586/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.