SCHEMBL25875551

SCHEMBL25875551

C=CC(=O)OCCCc1ccc(-c2ccc3c(c2)oc2c(C)c(OC(=O)C=C)ccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 3/20 0.38
HPGD P15428 5/20 0.34
KDM4E B2RXH2 5/20 0.34
HSD17B10 Q99714 2/20 0.34
GAA P10253 2/20 0.34
KMT2A Q03164 2/20 0.34
LMNA P02545 1/20 0.34
GLA P06280 1/20 0.34
MAPK1 P28482 1/20 0.34
MET P08581 5/20 0.34
ALDH1A1 P00352 3/20 0.34
TSHR P16473 2/20 0.34
AKR1B10 O60218 2/20 0.34
AKR1B1 P15121 2/20 0.34
MMP12 P39900 1/20 0.34
MMP13 P45452 1/20 0.34
THRA P10827 1/20 0.33
GBA1 P04062 1/20 0.32
MAPT P10636 2/20 0.32
ALOX5 P09917 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874108 0.92 THRB (0.38) THRBHPGDKDM4EHSD17B10GAA
SCHEMBL25875844 0.89 MET (0.37) THRBHPGDKMT2AMETALDH1A1
SCHEMBL25875291 0.89 THRB (0.35) THRBMETALDH1A1TSHRAKR1B10
SCHEMBL25875668 0.87 THRB (0.39) THRBHPGDKDM4EHSD17B10GAA
SCHEMBL25876380 0.86 THRB (0.34) THRBMETAKR1B10AKR1B1MMP12
SCHEMBL25875096 0.85 THRB (0.42) THRBHPGDKDM4EHSD17B10GAA
SCHEMBL25876638 0.85 THRB (0.33) THRBMETMMP12MMP13
SCHEMBL25875552 0.84 KDM4E (0.36) HPGDKDM4EHSD17B10GAAKMT2A
SCHEMBL25875457 0.84 KMT2A (0.38) THRBHPGDKDM4EHSD17B10GAA
SCHEMBL25874988 0.83 THRB (0.45) THRBHPGDKDM4EHSD17B10GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed