SCHEMBL25876380

SCHEMBL25876380

C=CC(=O)OCCCc1ccc(-c2ccc3c(c2)oc2c(C(F)(F)F)c(OC(=O)C=C)ccc23)cc1

nearest known ligand 0.34

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.34
NR1H2 P55055 1/20 0.33
NR1H3 Q13133 1/20 0.33
MMP12 P39900 1/20 0.32
MMP13 P45452 1/20 0.32
MET P08581 2/20 0.31
AKR1B10 O60218 1/20 0.31
AKR1B1 P15121 1/20 0.31
RXRA P19793 2/20 0.31
RXRB P28702 2/20 0.31
RXRG P48443 2/20 0.31
SYK P43405 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25874550 0.93 THRB (0.34) THRBNR1H2NR1H3METAKR1B10
SCHEMBL25875291 0.88 THRB (0.35) THRBMMP12MMP13METAKR1B10
SCHEMBL25876638 0.88 THRB (0.33) THRBMMP12MMP13MET
SCHEMBL25876564 0.87 THRB (0.35) THRBNR1H2NR1H3
SCHEMBL25875551 0.86 THRB (0.38) THRBMMP12MMP13METAKR1B10
SCHEMBL25875213 0.85 THRB (0.38) THRB
SCHEMBL25876385 0.85 THRB (0.33) THRBNR1H2NR1H3
SCHEMBL25876291 0.85 CYP2C9 (0.35) THRB
SCHEMBL25875844 0.85 MET (0.37) THRBMMP12MMP13METAKR1B10
SCHEMBL25876474 0.84 THRB (0.35) THRBNR1H2NR1H3MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed