SCHEMBL25875847

SCHEMBL25875847

C=CC(=O)Oc1ccc(-c2ccc3c(oc4c(OC)c(OC(=O)C=C)ccc43)c2F)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.38
MAOA P21397 4/20 0.36
MAOB P27338 3/20 0.36
THRB P10828 3/20 0.34
ALDH1A1 P00352 3/20 0.33
TYMS P04818 1/20 0.33
KDM4E B2RXH2 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
CYP3A4 P08684 2/20 0.33
MAPT P10636 2/20 0.33
LMNA P02545 1/20 0.33
TP53 P04637 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
GAA P10253 2/20 0.32
HTT P42858 1/20 0.32
TERT O14746 1/20 0.32
BACE1 P56817 1/20 0.32
MAPK1 P28482 1/20 0.31
TUBB4A P04350 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875376 0.92 ADORA3 (0.36) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25876143 0.91 ADORA3 (0.41) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25875988 0.88 ALDH1A1 (0.39) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25876640 0.88 ADORA3 (0.35) ADORA3THRBTYMS
SCHEMBL25875553 0.87 KMT2A (0.39) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25870131 0.87 ABL1 (0.38) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25876149 0.87 ADORA3 (0.36) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25873939 0.86 MAOA (0.41) MAOAMAOBTHRBALDH1A1TYMS
SCHEMBL25875982 0.85 MAOA (0.38) ADORA3MAOAMAOBTHRBALDH1A1
SCHEMBL25874471 0.84 KDM4E (0.44) MAOAMAOBTHRBALDH1A1TYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed