SCHEMBL25876144

SCHEMBL25876144

C=C(C)C(=O)Oc1ccc(-c2ccc3c(oc4c(OC)c(OC(=O)C(=C)C)ccc43)c2OC)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.41
ELANE P08246 1/20 0.39
MAOA P21397 4/20 0.38
MAOB P27338 3/20 0.38
BACE1 P56817 1/20 0.36
KMT2A Q03164 5/20 0.36
MEN1 O00255 3/20 0.36
ATM Q13315 1/20 0.36
ALDH1A1 P00352 4/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
MAPK1 P28482 1/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.35
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
GAA P10253 2/20 0.34
HTT P42858 1/20 0.34
TERT O14746 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25875672 0.92 KMT2A (0.43) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25875989 0.92 KMT2A (0.41) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25875982 0.91 MAOA (0.38) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25875377 0.91 MAOA (0.36) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25876790 0.91 ABL1 (0.38) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25876288 0.91 ABL1 (0.38) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25876482 0.88 ADORA3 (0.34) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25876151 0.88 ADORA3 (0.36) ADORA3ELANEMAOAMAOBBACE1
SCHEMBL25875104 0.86 ALDH1A1 (0.40) ELANEKMT2AMEN1ALDH1A1KDM4E
SCHEMBL25874472 0.86 MAOA (0.47) ELANEMAOAMAOBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023134594-A1 NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTAL COMPOSITION, OPTICAL ANISOTROPIER, AND LIQUID CRYSTAL DISPLAY COMPONENT 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed
WO-2023134595-A1 POLYMERIZABLE COMPOUND, COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE 烟台显华科技集团股份有限公司 2023-07-20 WO disclosed