Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.38 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25870571 | 0.87 | POLB (0.41) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL27381769 | 0.84 | POLB (0.55) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL25876507 | 0.82 | POLB (0.44) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL25870439 | 0.76 | POLB (0.47) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL25870433 | 0.76 | ALDH1A1 (0.48) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL22802079 | 0.75 | SMN1; SMN2 (0.43) | L3MBTL1POLBNPSR1KMT2APKM | |
| SCHEMBL27381767 | 0.75 | CYP2D6 (0.65) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL25870493 | 0.75 | POLB (0.50) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 | |
| SCHEMBL15490018 | 0.74 | SMN1; SMN2 (0.48) | ALDH1A1L3MBTL1POLBNPSR1KMT2A | |
| SCHEMBL25870730 | 0.73 | POLB (0.47) | ALDH1A1CYP2D6L3MBTL1POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023116920-A1 | PENTA- FUSED HEXA-HETEROCYCLIC COMPOUND, PREPARATION METHOD, PHARMACEUTICAL COMPOSITION AND USE | 杭州多域生物技术有限公司 | 2023-06-29 | — | — | WO | disclosed |