Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 1/20 | 0.46 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.46 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 4/20 | 0.42 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP9 | P14780 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | CETP | P11597 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25875229 | 0.94 | PRSS1 (0.48) | PRSS1PRSS2PRSS3TLR2MMP3 | |
| SCHEMBL25644954 | 0.91 | PRSS1 (0.46) | PRSS1PRSS2PRSS3TLR2MMP3 | |
| SCHEMBL25875656 | 0.90 | CYP3A4 (0.45) | PRSS1PRSS2PRSS3TLR2MMP3 | |
| SCHEMBL16826374 | 0.85 | CYP3A4 (0.49) | PRSS1PRSS2PRSS3TLR2ALDH1A1 | |
| SCHEMBL16826149 | 0.85 | CYP3A4 (0.49) | PRSS1PRSS2PRSS3TLR2ALDH1A1 | |
| SCHEMBL25869882 | 0.84 | LMNA (0.46) | PRSS1PRSS2PRSS3CYP3A4TSHR | |
| SCHEMBL31647809 | 0.83 | CYP3A4 (0.47) | PRSS1PRSS2PRSS3TLR2ALDH1A1 | |
| SCHEMBL25876320 | 0.83 | FAAH (0.45) | — | |
| SCHEMBL5076023 | 0.82 | ALDH1A1 (0.52) | PRSS1PRSS2PRSS3CETPALDH1A1 | |
| SCHEMBL5076609 | 0.82 | ALDH1A1 (0.52) | PRSS1PRSS2PRSS3CETPALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230348362-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2023-11-02 | — | — | US | disclosed |
| US-20230233468-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | Suzhou Abogen Biosciences Co., Ltd. (CN) | 2023-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230233468-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | CETP, NPC1, LCAT | PRSS1 3436/4885PRSS2 3879/4885PRSS3 3682/4885 |
| US-20230348362-A1 | LIPID COMPOUNDS AND LIPID NANOPARTICLE COMPOSITIONS | CETP, NPC1, LCAT | PRSS1 3436/4885PRSS2 3879/4885PRSS3 3682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.