Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | S100A4 | P26447 | 2/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.48 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.48 |
| ▸ | RELA | Q04206 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | HKDC1 | Q2TB90 | 4/20 | 0.47 |
| ▸ | TDP2 | O95551 | 4/20 | 0.47 |
| ▸ | BLM | P54132 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25882776 | 0.90 | MAP2K7 (0.63) | STAT3KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL6350632 | 0.77 | MAPT (0.59) | STAT3KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL30991488 | 0.74 | RAB9A (0.79) | STAT3KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL29249534 | 0.74 | RAB9A (0.79) | STAT3KMT2AMEN1RAB9ANPC1 | |
| SCHEMBL16297243 | 0.72 | MAPT (0.64) | KMT2AMEN1RAB9ANPC1MAP2K7 | |
| SCHEMBL15906854 | 0.72 | RAB9A (0.68) | KMT2AMEN1RAB9ANPC1MAP2K7 | |
| SCHEMBL30704433 | 0.72 | CYP19A1 (0.47) | KMT2AMEN1RAB9ANPC1MAP2K7 | |
| SCHEMBL15765691 | 0.70 | PRKCI (0.59) | KMT2AMEN1RAB9ANPC1MAPT | |
| SCHEMBL29633221 | 0.70 | MAPT (0.77) | KMT2AMEN1RAB9ANPC1MAP2K7 | |
| SCHEMBL28736228 | 0.70 | MAPT (0.77) | KMT2AMEN1RAB9ANPC1MAP2K7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |