Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.77 |
| ▸ | BLM | P54132 | 5/20 | 0.77 |
| ▸ | MEN1 | O00255 | 5/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.77 |
| ▸ | HTT | P42858 | 3/20 | 0.77 |
| ▸ | TDP2 | O95551 | 3/20 | 0.77 |
| ▸ | APAF1 | O14727 | 3/20 | 0.77 |
| ▸ | CASP3 | P42574 | 3/20 | 0.77 |
| ▸ | SENP8 | Q96LD8 | 3/20 | 0.77 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.77 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.77 |
| ▸ | HPGD | P15428 | 3/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.77 |
| ▸ | GAA | P10253 | 2/20 | 0.77 |
| ▸ | NSD2 | O96028 | 1/20 | 0.77 |
| ▸ | THRB | P10828 | 1/20 | 0.77 |
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28736228 | 1.00 | MAPT (0.77) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL13381749 | 0.87 | CASP3 (1.00) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL30991483 | 0.81 | MAPT (0.62) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL16296871 | 0.81 | MAPT (0.62) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL29633315 | 0.80 | MAPT (0.60) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL28736312 | 0.80 | MAPT (0.60) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL6350632 | 0.78 | MAPT (0.59) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL15689664 | 0.78 | RAB9A (0.57) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL13398556 | 0.78 | KMT2A (0.72) | MAPTKMT2ABLMMEN1LMNA | |
| SCHEMBL29633237 | 0.77 | RAB9A (1.00) | MAPTKMT2ABLMMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118271193-A | Method for promoting catalytic synthesis of 2-amino-1, 4-naphthoquinone compounds by using nicotinic acid as ligand and using dichloro-titanocene | 宁夏师范学院 | 2024-07-02 | — | — | CN | disclosed |
| CN-109748809-B | Method for synthesizing 2-substituted amino-1, 4-naphthoquinone derivative | 中国科学院成都有机化学有限公司 | 2022-05-13 | — | — | CN | disclosed |