Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | CASP3 | P42574 | 4/20 | 0.59 |
| ▸ | SENP8 | Q96LD8 | 4/20 | 0.59 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.59 |
| ▸ | SENP6 | Q9GZR1 | 4/20 | 0.59 |
| ▸ | APAF1 | O14727 | 4/20 | 0.59 |
| ▸ | HKDC1 | Q2TB90 | 4/20 | 0.59 |
| ▸ | TDP2 | O95551 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.59 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.59 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29633221 | 0.78 | MAPT (0.77) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL28736228 | 0.78 | MAPT (0.77) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL25876505 | 0.77 | STAT3 (0.53) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL6847129 | 0.77 | KMT2A (0.44) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL30991483 | 0.76 | MAPT (0.62) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL16296871 | 0.76 | MAPT (0.62) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL28736312 | 0.75 | MAPT (0.60) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL29633315 | 0.75 | MAPT (0.60) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL6845721 | 0.75 | STAT3 (0.43) | MAPTKMT2ACASP3SENP8SENP7 | |
| SCHEMBL25449209 | 0.75 | AKR1C3 (0.66) | MAPTKMT2AKDM4EMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6844353-B2 | Fungicidal properties of sampangine and its analogs to agriculturally important fungal plant pathogens | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2005-01-18 | — | — | US | disclosed |
| WO-2004086861-A2 | FUNGICIDAL PROPERTIES OF SAMPANGINE AND ITS ANALOGS TO AGRICULTURALLY IMPORTANT FUNGAL PLANT PATHOGENS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2004-10-14 | — | — | WO | disclosed |
| US-20040192721-A1 | Fungicidal properties of sampangine and its analogs to agriculturally important fungal plant pathogens | UNIVERSITY OF MISSISSIPPI, THE | 2004-09-30 | — | — | US | disclosed |
| EP-0588796-B1 | SAMPANGINE DERIVATIVES USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | UNIV MISSISSIPPI (US) | 2001-04-04 | — | — | EP | disclosed |
| EP-0556319-B1 | SAMPANGINE DERIVATIVES USEFUL AS ANTIFUNGAL AGENTS | UNIV MISSISSIPPI (US) | 2000-07-26 | — | — | EP | disclosed |
| US-5530004-A | ADMINISTERING SAMPANGINE AND CLEISTOPHOLINE ANALOGS | THE UNIVERSITY OF MISSISSIPPI (US) | 1996-06-25 | — | — | US | disclosed |
| EP-0588796-A4 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | UNIV MISSISSIPPI RES INST (US) | 1994-09-14 | — | — | EP | disclosed |
| EP-0588796-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1994-03-30 | — | — | EP | disclosed |
| EP-0556319-A4 | — | — | 1994-01-19 | — | — | EP | disclosed |
| EP-0556319-A1 | SAMPANGINE AND DERIVATIVES USEFUL AS ANTIFUNGAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-08-25 | — | — | EP | disclosed |
| US-5227383-A | Sampangine analogs | THE UNIVERSITY OF MISSISSIPPI (US) | 1993-07-13 | — | — | US | disclosed |
| WO-1992022297-A1 | NEW COMPOUNDS AND COMPOSITIONS USEFUL AS ANTIFUNGAL AND ANTIMYCOBACTERIAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-12-23 | — | — | WO | disclosed |
| US-5128344-A | SAMPANGINE AND DERIVATIVES USEFUL AS AN ANTIFUNGAL AGENT | UNIVERSITY OF MISSISSIPPI (US) | 1992-07-07 | — | — | US | disclosed |
| WO-1992007565-A1 | SAMPANGINE AND DERIVATIVES USEFUL AS ANTIFUNGAL AGENTS | THE UNIVERSITY OF MISSISSIPPI (US) | 1992-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040192721-A1 | Fungicidal properties of sampangine and its analogs to agriculturally important fungal plant pathogens | SAMSN1, SAMHD1, SPIN4 | MAPT 2164/4885KMT2A 2997/4885CASP3 711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.