SCHEMBL25876649

SCHEMBL25876649

Cc1ccc(/N=C(\c2ccccc2)c2cccc(/C(=N/c3ccc(C)cc3Br)c3ccccc3)n2)c(Br)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 6/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
KMT2A Q03164 4/20 0.38
NPC1 O15118 4/20 0.38
RAB9A P51151 4/20 0.38
MEN1 O00255 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
HSP90AA1 P07900 1/20 0.38
ALDH1A1 P00352 7/20 0.38
GAA P10253 1/20 0.36
NFKB1 P19838 1/20 0.36
NFKB2 Q00653 1/20 0.36
RELA Q04206 1/20 0.36
HTT P42858 2/20 0.35
LMNA P02545 1/20 0.35
TP53 P04637 1/20 0.33
HPGD P15428 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19887500 0.86 KMT2A (0.41) MAPTSMN1; SMN2KMT2ANPC1RAB9A
SCHEMBL5587353 0.86 KMT2A (0.41) MAPTSMN1; SMN2KMT2ANPC1RAB9A
SCHEMBL5588691 0.84 KMT2A (0.40) MAPTSMN1; SMN2KMT2ANPC1RAB9A
SCHEMBL21078307 0.83 ESR1 (0.38) MAPTSMN1; SMN2KMT2ANPC1RAB9A
SCHEMBL25876652 0.82 NOS3 (0.37) MAPTSMN1; SMN2KMT2AMEN1HSP90AA1
SCHEMBL5589912 0.81 ALDH1A1 (0.36) MAPTSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL25876650 0.81 SIGMAR1 (0.43) MAPTSMN1; SMN2NPC1RAB9AALDH1A1
SCHEMBL5587745 0.80 ALDH1A1 (0.36) MAPTSMN1; SMN2KMT2AMEN1ALDH1A1
SCHEMBL21078311 0.80 MAPT (0.42) MAPTSMN1; SMN2KMT2ANPC1RAB9A
SCHEMBL25647091 0.80 ALDH1A1 (0.35) MAPTSMN1; SMN2KMT2ANPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11712687-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-01 US disclosed
US-11712687-B2 Catalyst systems and polymerization processes for using the same EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-01 US disclosed