Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1300124 | 0.86 | MAPT (0.47) | NOD1TSHRMAPTSLC15A1DPP7 | |
| SCHEMBL27869324 | 0.80 | DPP7 (0.44) | NOD1SLC15A1DPP7 | |
| SCHEMBL31718803 | 0.80 | NOD1 (0.51) | NOD1MAPTDPP7 | |
| SCHEMBL19547634 | 0.80 | DPP7 (0.44) | NOD1SLC15A1DPP7 | |
| SCHEMBL1301293 | 0.80 | MAPT (0.37) | TSHRMAPTSLC15A1DPP7P2RY10 | |
| SCHEMBL7985007 | 0.79 | CA2 (0.49) | TSHRMAPTHCAR2ALDH1A1TRPV1 | |
| SCHEMBL453102 | 0.79 | SLC1A2 (0.41) | NOD1TSHRHCAR2DPP7ALDH1A1 | |
| SCHEMBL1096747 | 0.79 | SLC1A2 (0.41) | NOD1TSHRHCAR2DPP7ALDH1A1 | |
| SCHEMBL5670259 | 0.79 | GSR (0.52) | NOD1DPP7 | |
| SCHEMBL6432150 | 0.79 | GSR (0.52) | NOD1DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563926-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | Genomatica, Inc. (US) | 2013-03-06 | — | — | EP | disclosed |
| WO-2011137198-A1 | MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF PROPYLENE | GENOMATICA, INC. (US) | 2011-11-03 | — | — | WO | disclosed |